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EMD Chemicals Seminars
EMD Chemicals can provide our customers
useful, technical seminars on a wide range of topics. The seminars are
presented by experts in these areas. Each seminar can be customized for
your special needs. For additional seminar information and scheduling, please
contact your local
EMD Chemicals Sales Representative.
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| Biotechnology |
Proteome Technologies
Peptide, DNA & RNA Synthesis and New Applications
Solvent Scaleup
From Laboratory to commercial scale solvent usage;
how the EM ReCycler® Container Program can
help you? |
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| High Purity
Solvents |
Troubleshooting High Purity Solvents for Use in Environmental
Analysis.
This presentation examines inherent and acquired impurities of
solvents used in gas chromatography and environmental analysis.
Acetone, dichloromethane, hexane and other solvents will be reviewed.
Inherent by-products, degradation/oxidation phenomena will be
discussed.
Troubleshooting High Purity Solvents for Use in Gas and Liquid
Chromatography.
Solvents used in chromatography are typically purified for specific
applications, i.e. UV transparency, ECD responsive substances, etc.
The types of interferences and their responsiveness to these detectors
vary by multiple orders of magnitude. This presentation examines and
discusses potential interferences associated with solvents used in
HPLC and GC. |
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| Karl
Fischer |
KF I - Introduction to Karl Fisher Titration Principles and
Routine Practice
This entry-level seminar will review the development and principles of Karl
Fischer titration. A brief discussion of KF titration history, principles,
and comparative advantages will be followed by an in-depth review of the
two types of KF, volumetry and coulometry, including an overview of the
differences between one-component and two-component volumetric titration,
as well as between conventional and fritless-cell coulometric titration.
Guidelines for selecting the appropriate KF instrumentation will be presented.
Titration using indirect techniques, such as oil evaporators and KF-Ovens will
also be addressed.
KF II - Advanced Karl Fisher Titration Principles and Applications
This seminar geared to practicing KF users will cover a number of more
advanced topics in KF analysis with an emphasis on developing a fundamental
understanding of sample and KF reagent chemistries. Following a comprehensive
review of common KF reagent issues, a systematic approach to proper reagent
selection, sample size selection, and auxiliary equipment selection for
problematic sample types will be presented and illustrated using practical
examples. The use of water standards for instrument validation and control
will be highlighted. Finally, best practices for sample handling, weighing,
and transfer to the titration cell will be briefly reviewed.
Reagent Selection in Karl Fisher Analysis
Over the years, moisture analysis by Karl Fischer (KF) titration has
progressed from an esoteric laboratory procedure to a widely accepted
automated method routinely used in a variety of industries. Despite the
development of reliable state-of-the-art titrators, the key to successful
KF remains the fundamental understanding of sample and KF reagent chemistries.
This seminar will present a systematic approach to proper reagent selection,
sample size selection, and auxiliary equipment selection for several
commercially important classes of materials.
Karl Fischer Reagent and Instrument Selection for Successful Analysis of
Petrochemical Products
Karl Fischer (KF) titration is the most versatile and established automated
method for moisture determination in a variety of sample types. However,
crude oil and various petroleum products, such as lubrication oils, are
either insoluble in traditional KF solvents, or typically contain compounds
known to interfere with the KF analysis. This seminar will address how
selection of the most appropriate reagents, co-solvents, standards, and
auxiliary instrumentation can ensure success in analyzing crude oil and
petroleum products for water content using KF titration.
Karl Fischer Moisture Analysis in Pharmaceutical Samples
Performing moisture analysis on pharmaceutical samples can present many
challenges to the KF analyst. Expensive ingredients often require testing to
be performed with very small amounts of sample. Additionally, many compounds
of pharmaceutical importance undergo interfering side reactions with the Karl
Fischer reagent. Yet other compounds are known to hinder KF analysis due to
their excessively high or low pH. In all such cases, it can be quite difficult
to perform accurate water determination by KF titration. This seminar will
focus on specific reagents, instrumentation, and techniques designed to optimize
moisture analysis of pharmaceuticals. Included in the discussion will be
methods for testing lyophilized powders, creams, as well as liquid-based
pharmaceutical products.
Avoiding Common Pitfalls in Karl Fischer Analysis
Karl Fischer (KF) titration is commonly used to determine water content in
many product types. Errors in KF analysis may arise from a variety of sources.
Following a brief review of the most common sources of error in KF titration,
this seminar will provide specific strategies to minimize errors due to:
• Choice of instrument
• Choice of reagents
• Titration cell set-up/preparation
• Sample weighing technique
• Sample handling technique
• Sample addition technique
• Side reactions
Validation and Control of KF Titrators
Karl Fischer (KF) titration is an analytical technique frequently used in
Quality Assurance (QA). Various regulatory guidelines (e.g., GLP, ISO) call
for validation of QA test equipment to insure that the equipment produces
accurate and reproducible results, meaning that the analyst must continuously
check and document the performance of his KF instrument using specially
formulated water standards. Records from such performance checks substantiate
the sample test results obtained from the titrator. Therefore, the focus of
this seminar will be on standards, procedures, documentation, and best practices
used for instrument validation and control. Additionally, the use of standards
to validate KF-Ovens and Oil Evaporators will also be addressed. |
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| Safety |
Chemical Handling Safety Seminars
These 30-45 minute seminar cover various aspects of safe chemical handling in
industrial facilities and laboratories. Perfect for new employees,
university students, or as a refresher course, these training courses include
a 20 minute DVD presentation along with pre-and post-content quizzes,
summary takeaways and a certificate of completion for each employee.
Chemical Handling Safety - The Basics
Refresher training course on basic precautions and hazards present
when handling chemicals.
Chemical Handling Safety - Solvents
Explains particular hazards present when handling solvents as well
as appropriate containment and first aid procedures in case of spills.
Chemical Handling Safety - Corrosives
Many common chemicals have corrosive properties. This seminar is designed to
explain hazards and first aid for such chemicals.
Chemical Handling Safety - Flammables
In addition to exposure hazards, many chemicals pose a threat to the immediate
surroundings of persons handling them. The handling of flammables safely is
discussed as well as procedures to follow in an emergency. |
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