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176903  Anthrax Lethal Factor Protease Substrate II, Colorimetric

Anthrax LF Protease Substrate II, Colorimetric, Bacillus anthracis LF Protease Substrate II, Colorimetric

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08 February 2012

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176903-1MG  1 mg 
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An N-acetylated, C-p-nitroanilide (pNA) derivative of a 14-mer peptide substrate designed from the MEK-2 template that is useful for measuring Anthrax lethal factor (LF) metalloproteolytic activity with a detection limit of ~100 pM. The release of pNA is monitored by recording the absorption at ~405 nm (ε405 = 9,920 M-1cm-1). Reported to be useful for high-throughput screening of LF inhibitors.
Product information
Peptide Sequence Ac-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-pNA
Form Lyophilized
Formulation Supplied as a trifluoroacetate salt.
Molar mass 2089.5
Protect from Light Yes
Hygrocopic Yes
Packaged under inert gas Yes
Purity ≥97% by HPLC
Solubility H2O or 5% Acetic Acid
Chemical formula C87H153N43O18
Store and ship information
Storage -20°C
Ship Blue Ice Only
Standard Handling

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© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.

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