For general questions please contact our Customer Service:
EMD Chemicals, Inc.
480 S. Democrat Road
08027 Gibbstown
United States
Phone: 800 854 3417
Fax: 800 776 0999
E-mail: Customer.CareDesk@emdchemicals.com
08 February 2012
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This product has been discontinued.
Please refer to our complete listing of apoptosis inducers for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A cell-permeable pyridyl compound that selectively promotes apoptosome formation and the subsequent caspase activation by antagonizing prothymosin-α (ProT), a negative regulator of mitochondria-initiated caspase activation. Shown to elevate caspase-3 activity in cancer cell extracts in a dose-dependent manner (maximum stimulation at ~ 100 to 200 µM in HeLa cell lysate).
| Product information | |||
|---|---|---|---|
| Form | Beige solid | ||
| Molar mass | 240.5 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO, MeOH, or Dilute HCl | ||
| Chemical formula | C8H8Cl3NO | ||
| CAS number | 10129-56-3 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Carcinogenic / Teratogenic |
||
