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EMD Chemicals, Inc.
480 S. Democrat Road
08027 Gibbstown
United States
Phone: 800 854 3417
Fax: 800 776 0999
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08 February 2012
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A synthetic substrate specific for Ca2+/calmodulin-dependent protein kinase II (CaMK II). The substrate sequence is based on the CaMKII pseudosubstrate core found within the autoinhibitory domain of the enzyme. Autophosphorylation of Thr286 within the autoinhibitory domain traps bound calmodulin by greatly reducing its dissociation rate, thus prolonging the active state.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | H-Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH | ||
| Form | Lyophilized | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Molar mass | 1508.7 | ||
| Hygrocopic | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | H2O | ||
| Chemical formula | C65H113N21O20 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
