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196355  Bak BH3 Fusion Peptide, Cell-Permeable, Negative Control

H-RQIKIWFQNRRMKWKKMGQVGRQAAIIGDDINRRY-OH, Ant-BH3-A78

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08 February 2012

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This product is currently discontinued or not available.
A cell-permeable, Antennapedia-BH3 (Bcl-2 homology 3 domain from Bak) mutated (Leu78 replaced by Ala) fusion peptide analog of Ant-BH3 (Cat. No. 196350) that may be useful as a negative control. Shown to be defective in binding to Bcl-xL. Has little to no apoptotic effect.
Product information
Peptide Sequence H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Met-Gly-Gln-Val-Gly-Arg-Gln-Ala-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg-Arg-Tyr-OH
Form Off-white lyophilized solid
Formulation Supplied as a trifluoroacetate salt.
Molar mass 4362.2
Hygrocopic Yes
Packaged under inert gas Yes
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C193H315N65O47S2
Store and ship information
Storage -20°C
Ship Ambient Temperature Only
Standard Handling

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© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.

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