251405
D-24851
N-(Pyridin-4-yl)-[1-(4-chlorobenzyl)-indol-3-yl]-glyoxyl Amide
For general questions please contact our Customer Service:
EMD Chemicals, Inc.
480 S. Democrat Road
08027 Gibbstown
United States
Phone: 800 854 3417
Fax: 800 776 0999
E-mail: Customer.CareDesk@emdchemicals.com
08 February 2012
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This product has been discontinued.
Please refer to our complete listing of extracellular matrix and adhesion tools for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A cell-permeable, potent anticancer agent that destabilizes microtubules in tumor cells as well as in a cell-free system. Binds directly to tubulin and inhibits polymerization (IC50 = 300 nM). Also blocks cell cycle at G2/M phase, shows efficacy toward multidrug-resistant (MDR) tumor cells, and shows no neurotoxicity.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Molar mass | 389.8 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C22H16ClN3O2 | ||
| CAS number | 204205-90-3 | ||
| Declaration | Indibulin (Cat #251405) is the subject matter of patents and patent applications assigned to ZIOPHARM Oncology, Inc. Indibulin is made available only on the following conditions: 1. Indibulin is to be used for noncommercial research purposes only (which shall not include for therapeutic or diagnostic purposes or for human use) and shall not be used to help create analogs or derivatives of indibulin. If indibulin is used for any of the above proscribed uses, any resulting intellectual property shall belong to ZIOPHARM Oncology, Inc. and your laboratory will sign any documents necessary to effectuate this result. A license is required for any commercial use, including use of indibulin for production purposes by any commercial entity. Information about commercial licenses may be obtained from ZIOPHARM Oncology, Inc. 1 First Avenue, Parris Building #34, Navy Yard Plaza, Boston, MA 02129, Attention: Legal Department. 2. Indibulin (and any portions or derivatives thereof) may not be distributed to third parties outside of your laboratory, unless the recipient receives a copy of this assurance letter and agrees to be bound by its terms. 3. The initial purchaser may refuse to accept the above conditions by returning the kit unopened and the enclosed materials unused. By accepting or using the kit or the enclosed materials, you agree to be bound by the foregoing conditions. Sold under license of U.S. Patent 6,008,231 and related patents. | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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