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71194  0.5 M THP Solution

Reducing agent compatible with His•Bind® chromatography

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EMD Chemicals, Inc.
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09 February 2012

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Product number Size Quantity Price / Available to Ship
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71194-3  1 ml 
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71194-4  5 ml 
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Prices are subject to change without notice.

THP [Tris(hydroxypropyl)phosphine; C9H21O3P] is a water-soluble, odorless, sulfhydryl reducing agent that is more stable and effective than dithiothreitol (DTT). Against oxidized glutathione, the reducing capacity of THP (0.232 meq/g) is greater than that of TCEP (0.182 meq/g). THP is also more resistant to air oxidation than DTT and is compatible with immobilized metal affinity chromatography with His•Bind® and Ni-NTA His•Bind resins at concentrations up to 1.0 mM. The common working concentration of THP for many applications is 1–5 mM. THP is provided as a ready-to-use 0.5 M solution in water.

Purity: > 80% by NMR. CAS: 4706-17-6. MW: 208.2.


Store and ship information

Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Storage -20°C
Ship Blue Ice Only
Corrosive

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© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.

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