230751
Chromeceptin
2-Amino-3-cyano-4-(3-trifluoromethylphenyl)-7-(N,N-dimethylamino)-chrom-2-ene, 94G6
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EMD Chemicals, Inc.
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09 February 2012
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A cell-permeable benzochromene compound that blocks insulin-induced adipogenesis in 3T3-L1 cells (100% blockage at ≤ 20 ng/µl) and selectively suppresses IGF2- (insulin-like growth factor 2) dependent growth of HepG2 carcinoma cells (IC50 = 29 nM). Shown to bind to MFP-2 (multifunctional protein-2) and activate STAT6-mediated gene expression, such as IGFBP-1 and SOCS-3, in HepG2 cells.
| Product information | |||
|---|---|---|---|
| Form | Brown solid | ||
| Molar mass | 359.4 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO or MeOH | ||
| Chemical formula | C19H16F3N3O | ||
| CAS number | 331859-86-0 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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