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Peptide & HT Organic Synthesis Resource Center

Non-explosive Replacement for HOBt

Oxyma Pure is an excellent non-explosive replacement for HOBt in carbodiimide-mediated coupling reactions.

Oxyma Pure:

  • can be used in place of HOBt in carbodiimide-mediated coupling reactions without change of protocol
  • gives results comparable to HOAt in step-wise solid phase synthesis
  • less epimerization than HOBt in fragment condensation reactions

For more information, download Innovations 02/09.

Merck:/topic/novabiochem/oxyma.jpg

Product Cat. No.
Oxyma Pure 851086

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© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.

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