129935
Actinomycin D, 7-Amino-
7-AAD, 7-Amino-AMD, 7-Aminoactinomycin C1, 7-Aminodactinomycin
7-Aminoactinomycin D, like its parent molecule, actinomycin D, is a DNA intercalator and has antibacterial properties. Exhibits growth-inhibitory activity against certain leukemias and sarcomas. Fluorescent excitation and emission maxima are 500 and 672 nm, respectively. Complexes with DNA and absorbs at 555 nm and emits at 655 nm. Useful in distinguishing early apoptotic cells, which have lost membrane integrity, from apoptotic and live cells. Has been used in DNA analysis and as a probe for chromosome structure and function.
| Product information | |||
|---|---|---|---|
| Form | Reddish-purple solid | ||
| Primary Target | leukemias and sarcomas | ||
| Molar mass | 1270.4 | ||
| Protect from Light | Yes | ||
| Hygrocopic | Yes | ||
| Purity | ≥85% by HPLC | ||
| Sample type | Intact Cells | ||
| Solubility | DMSO or EtOH | ||
| Chemical formula | C62H87N13O16 | ||
| RTECS | AU1579000 | ||
| CAS number | 7240-37-1 | ||
| Merck USA index | 14, 2800 | ||
| Store and ship information | |||
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<b>Hazardous Materials Attention:</b> Due to the nature of the Hazardous Materials in this shipment, additional shipping charges <i>may</i> be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Highly Toxic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36/37-45-28 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
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| R Phrase |
R: 28 Very toxic if swallowed. |
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