407240
Insulin-Like Growth Factor-I, Human, Recombinant, E. coli
rhIGF-I, Somatomedin-C
Recombinant, human insulin-like growth factor-I (70 amino acids) expressed in E. coli. Has about 40% homology to insulin and produces metabolic effects similar to insulin. Acts as an important local regulator of bone formation. Increases bone formation and bone resorption. Also inhibits etoposide-induced apoptosis in BALB/c 3T3 cells. Stimulates the activity of protein tyrosine kinases in both normal and diethylstilbestrol-treated hamster kidneys. Primarily involved in response of cells to growth hormones.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Molar mass | 7500 | ||
| Biological activity | ED50 = 0.3-1.5 ng/ml as measured in a cell proliferation assay with MCF-7 human breast carcinoma cells. | ||
| Purity | ≥97% by SDS-PAGE | ||
| Contaminants | Endotoxin: ≤1 EU/µg IGF-I | ||
| Solubility | Sterile PBS | ||
| RTECS | NM8905000 | ||
| CAS number | 67763-96-6 | ||
| Merck USA index | 14, 4986 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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