Native platelet-derived growth factor from human platelets. Consists of approximately 70% PDGF-AB and 30% PDGF-BB. PDGF action is mediated by cell surface α- and β-receptors. M.W. 28,000-32,000.
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Product information
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Form
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Lyophilized
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Formulation
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Lyophilized from sterile-filtered 25% acetonitrile, 0.1% TFA.
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Biological activity
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ED50 = 1-3 ng/ml as measured in a mitogenic assay using quiescent NR 6-3T3 fibroblasts
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Purity
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≥97% by SDS-PAGE
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Contaminants
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Endotoxin: ≤1 EU/µg PDGF
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Source
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Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
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Solubility
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Sterile 4 mM HCl containing at least 0.1% HSA or BSA
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Merck USA index
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14, 7525
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Store and ship information
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Storage
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-20°C
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Ship
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Ambient Temperature Only
Standard Handling
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