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559400  SB 203580, Iodo-

4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole

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09 February 2012

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559400-1MG  1 mg 
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A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase. Exhibits similar inhibitory potency as its parent compound SB 203580 (Cat. No. 559389). Useful for the identification of inhibitor binding sites in p38 MAP kinase.
Alternatives
559395 SB 203580, Hydrochloride
559389 SB 203580
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Alternative products for SB 203580, Iodo-
559395 SB 203580, Hydrochloride
559389 SB 203580
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Accessories forSB 203580, Iodo-
Product information
Form Off-white solid
Primary Target P38MAPK
Primary Target IC50 34 nM
Secondary target THP-1 (IC50 = 50-100 nM)
Molar mass 485.3
Protect from Light Yes
Cell permeable Yes
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C21H16IN3OS
CAS number 189319-35-5
Store and ship information
Storage -20°C
Ship Ambient Temperature Only
Standard Handling
SB 203580, Iodo-, molecular structure

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© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.

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