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Our Core Technologies are the Key to Your Success
From chiral synthesis to sophisticated organometallic reactions

With a broad technology platform, we deliver a complete matrix of production technologies to fulfill more than 95% of all common chemical reactions.

We offer specific expertise and equipment for:
Hydrogenation with homogeneous and heterogeneous catalysts, especially with stereoselectivity
Catalysis with various reaction gases (acid/base catalyzed couplings)
Organometallic reactions (lithiation, Grignard, Suzuki and others)
APIs manufacturing for parenteral applications
Compounds related to advanced drug release (for PEGylation and liposome techniques)
Scale-up, process improvement and implementation of routine production

Our state-of-the-art production equipment allows quick expansion of scale and we manage all cGMP related issues (e.g., change control and process qualification). With impeccable standards, you can rest assured that we are fully committed to your project.

Core reaction technologies include:
Chemical and catalytic reductions
Cross-coupling reactions (Suzuki, Heck, etc)
Cyanations
Friedel Crafts
Halogenations
Hydrogenations (up to 9 bars in a 3000 L reactor / up to 200 bars in a 1,600 L reactor -    homogenous and heterogenous catalysis)
Isomerisation Lithiations (BuLi, LDA, LiHMDS, etc)
Methylations (Dimethylsulfate)
Nitration (1,500 L reactor)
Organometallic chemistries (Grignards, Li-alkyles, LDA, DIBAH, LiAlH4, NaBH4, etc)
Rearrangements (Fries, Baeyer Villinger, etc)
Reductive aminations
Ritter reactions
Stereospecific reactions
Sulphur chemistries
Transmetalations
Willgerodt reactions
Wittig reactions
Wolff-Kishner reactions


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EMD Chemicals is Merck KGaA, Darmstadt, Germany, in the US and Canada.