Fractogel EMD process resin has been used for more than 10 years
and is widely-used in industry by biopharmaceutical companies, both large
and small, in various development and commercial-scale applications for the
purification of antibodies, peptides and other biomolecules. The semi-rigid
property of the resin bead offers enhanced process throughput and
the tentacle chemistry to which the function groups are attached to
provides superior
binding capacity and resolution compared to other media. Fractogel EMD media
binds very efficiently to proteins, nucleic acids and viruses.
Additionally, due to the tighter binding of the target molecule, Fractogel EMD
can also be used during the initial capture step of downstream processing. Its
ion exchangers perform better than non-tentacle resins due to greater
accessibility of the functional groups. The resin is robust under typical
operating and cleaning conditions and can be used over many cycles.